Takizawa, K;
Takagi, H;
Torii, R;
Tezduyar, TE;
Xu, XY;
(2014)
Coronary arterial dynamics computation with medical-image-based time-dependent anatomical models and element-based zero-stress state estimates.
Computational Mechanics
, 54
(4)
pp. 1047-1053.
10.1007/s00466-014-1049-6.
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Abstract
We propose a method for coronary arterial dynamics computation with medical-image-based time-dependent anatomical models. The objective is to improve the computational analysis of coronary arteries for better understanding of the links between the atherosclerosis development and mechanical stimuli such as endothelial wall shear stress and structural stress in the arterial wall. The method has two components. The first one is element-based zero-stress (ZS) state estimation, which is an alternative to prestress calculation. The second one is a "mixed ZS state" approach, where the ZS states for different elements in the structural mechanics mesh are estimated with reference configurations based on medical images coming from different instants within the cardiac cycle. We demonstrate the robustness of the method in a patient-specific coronary arterial dynamics computation where the motion of a thin strip along the arterial surface and two cut surfaces at the arterial ends is specified to match the motion extracted from the medical images. © 2014 The Author(s).
| Type: | Article |
|---|---|
| Title: | Coronary arterial dynamics computation with medical-image-based time-dependent anatomical models and element-based zero-stress state estimates |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s00466-014-1049-6 |
| Publisher version: | http://dx.doi.org/10.1007/s00466-014-1049-6 |
| Additional information: | © The Author(s) 2014. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
| Keywords: | Coronary arterial dynamics Time-dependent anatomical model Medical-image-based data Coronary atherosclerosis Element-based zero-stress state estimate Mixed zero-stress state |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1435064 |
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