UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Clinical diagnostic criteria for dementia associated with Parkinson's disease

Emre, M; Aarsland, D; Brown, R; Bum, DJ; Duyckaerts, C; Mizuno, Y; Broe, GA; ... Dubois, B; + view all (2007) Clinical diagnostic criteria for dementia associated with Parkinson's disease. MOVEMENT DISORD , 22 (12) 1689 - 1707. 10.1002/mds.21507.

Full text not available from this repository.

Abstract

Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD-D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD-D. The Task Force members were assigned to sub-committees and performed a systematic review of the literature, based on pre-defined selection criteria, in order to identify the epidemiological, clinical, auxillary, and pathological features of PD-D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point-prevelance is close to 30%, older age and akinetic-rigid form are associated with higher risk. PD-D is characterized by impairment in attention, memory, executive and visuo-spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body-type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD-D are proposed. (C) 2007 Movement Disorder Society.

Type: Article
Title: Clinical diagnostic criteria for dementia associated with Parkinson's disease
DOI: 10.1002/mds.21507
Keywords: Parkinson's disease, dementia, Parkinson's disease dementia, diagnosis, diagnostic criteria, CARDIAC SYMPATHETIC DENERVATION, PROGRESSIVE SUPRANUCLEAR PALSY, SLEEP BEHAVIOR DISORDER, CEREBRAL-BLOOD-FLOW, BRADYKINETIC-RIGID SYNDROMES, MULTIPLE SYSTEM ATROPHY, DATA-DRIVEN APPROACH, LEWY BODY DEMENTIA, ALZHEIMERS-DISEASE, COGNITIVE IMPAIRMENT
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
URI: http://discovery.ucl.ac.uk/id/eprint/142889
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item