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Indian Asians have poorer cardiovascular autonomic function than Europeans: this is due to greater hyperglycaemia and may contribute to their greater risk of heart disease

Bathula, R; Hughes, AD; Panerai, R; Potter, J; Thom, SA; Francis, DP; Shore, AC; ... Chaturvedi, N; + view all (2010) Indian Asians have poorer cardiovascular autonomic function than Europeans: this is due to greater hyperglycaemia and may contribute to their greater risk of heart disease. Diabetologia , 53 (10) 2120 - 2128. 10.1007/s00125-010-1818-5.

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Abstract

A high prevalence of diabetes contributes to excess CHD in Indian Asians, but the underlying mechanisms are unclear. Heart rate, heart rate variability (HRV) and baroreflex sensitivity (BRS) are measures of cardiac autonomic function that are disturbed by hyperglycaemia and predict CHD. We compared these measures in Indian Asians and Europeans, and sought explanations for the observed differences.

Type: Article
Title: Indian Asians have poorer cardiovascular autonomic function than Europeans: this is due to greater hyperglycaemia and may contribute to their greater risk of heart disease
Location: Germany
DOI: 10.1007/s00125-010-1818-5
Publisher version: http://dx.doi.org/10.1007/s00125-010-1818-5
Language: English
Keywords: Adult, Aged, Asian Continental Ancestry Group, Autonomic Nervous System, Baroreflex, Blood Glucose, Blood Pressure, Chi-Square Distribution, Electrocardiography, European Continental Ancestry Group, Female, Heart Diseases, Heart Rate, Humans, Hyperglycemia, Male, Middle Aged, Questionnaires, Regression Analysis, Risk Factors
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
URI: http://discovery.ucl.ac.uk/id/eprint/1428186
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