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A novel GC-rich dispersed repeat sequence in Drosophila melanogaster.

Flavell, AJ; Dyson, J; Ish-Horowicz, D; (1987) A novel GC-rich dispersed repeat sequence in Drosophila melanogaster. Nucleic Acids Res , 15 (10) pp. 4035-4048. 10.1093/nar/15.10.4035. Gold open access

Abstract

A novel family of dispersed repeat sequences from Drosophila melanogaster is described. Sequence analysis of two members of this family show them to contain greater than 75% GC bases. These are comprised of multiple repeats of GGX triplets interspersed occasionally with CGPy and TTPy. Southern blotting shows that these repeats are not transposable elements. Twenty four homologous recombinants have been localised by in situ hybridization to seven sites in the Drosophila genome. Polyadenylated RNAs homologous to this repeat family are expressed in a complex pattern which is developmentally regulated. We suggest that this family encodes a set of glycine-rich domains in Drosophila proteins.

Type: Article
Title: A novel GC-rich dispersed repeat sequence in Drosophila melanogaster.
Location: England
Open access status: An open access publication
DOI: 10.1093/nar/15.10.4035
Keywords: Animals, Codon, Drosophila melanogaster, Glycine, Poly A, Protein Conformation, RNA, Messenger, Recombination, Genetic, Repetitive Sequences, Nucleic Acid
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1425943
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