Topographical Functional Connectivity Pattern in the Perisylvian Language Networks.
549 - 560.
We performed a resting-state functional connectivity study to investigate directly the functional correlations within the perisylvian language networks by seeding from 3 subregions of Broca's complex (pars opercularis, pars triangularis, and pars orbitalis) and their right hemisphere homologues. A clear topographical functional connectivity pattern in the left middle frontal, parietal, and temporal areas was revealed for the 3 left seeds. This is the first demonstration that a functional connectivity topology can be observed in the perisylvian language networks. The results support the assumption of the functional division for phonology, syntax, and semantics of Broca's complex as proposed by the memory, unification, and control (MUC) model and indicated a topographical functional organization in the perisylvian language networks, which suggests a possible division of labor for phonological, syntactic, and semantic function in the left frontal, parietal, and temporal areas.
|Title:||Topographical Functional Connectivity Pattern in the Perisylvian Language Networks|
|Keywords:||Broca's complex, functional organization, pars opercularis (BA 44), pars orbitalis (BA 47), pars triangularis (BA 45), EVENT-RELATED FMRI, TRANSCRANIAL MAGNETIC STIMULATION, INFERIOR PREFRONTAL CORTEX, RESTING HUMAN BRAIN, SHORT-TERM-MEMORY, SENTENCE COMPREHENSION, BROCAS AREA, SEMANTIC SYSTEM, WORKING-MEMORY, TEMPORAL-LOBE|
|UCL classification:||UCL > School of BEAMS > Faculty of Engineering Science > Computer Science|
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