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Enhance, delete, incept: Manipulating hippocampus-dependent memories.

Spiers, HJ; Bendor, D; (2014) Enhance, delete, incept: Manipulating hippocampus-dependent memories. Brain Res Bull , 105 pp. 2-7. 10.1016/j.brainresbull.2013.12.011. Green open access

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Abstract

Here we provide a brief overview of recent research on memory manipulation. We focus primarily on memories for which the hippocampus is thought to be required due to its central importance in the study of memory. The repertoire of methods employed is expanding and includes optogenetics, transcranial stimulation, deep brain stimulation, cued reactivation during sleep and the use of pharmacological agents. In addition, the possible mechanisms underlying these memory changes have been investigated using techniques such as single unit recording and functional magnetic resonance imaging (fMRI). This article is part of a Special Issue entitled 'Memory enhancement'.

Type: Article
Title: Enhance, delete, incept: Manipulating hippocampus-dependent memories.
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.brainresbull.2013.12.011
Publisher version: http://dx.doi.org/10.1016/j.brainresbull.2013.12.0...
Additional information: © 2013 The Authors. Published by Elsevier Inc. All rights reserved. This is an open-access article distributed under the terms of the CreativeCommons Attribution License, which permits unrestricted use, distribution andreproduction in any medium, provided the original author and source are credited.
Keywords: Extinction, Fear conditioning, Hippocampus, Memory consolidation, Reconsolidation, Sleep
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Experimental Psychology
URI: https://discovery.ucl.ac.uk/id/eprint/1413219
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