Batchelor, AM; Knopfel, T; Gasparini, F; Garthwaite, J; (1997) Pharmacological characterization of synaptic transmission through mGluRs in rat cerebellar slices. NEUROPHARMACOLOGY , 36 (3) 401 - 403.
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The mGluR-mediated EPSP at parallel fibre-Purkinje cell synapses in the cerebellum was blacked concentration-dependently and reversibly by antagonists acting selectively on group-I mGluRs but not by an inhibitor of group-III receptors. The results provide pharmacological evidence that the receptor type responsible for the mGluR-EPSP is mGluR1. (C) 1997 Elsevier Science Ltd.
|Title:||Pharmacological characterization of synaptic transmission through mGluRs in rat cerebellar slices|
|Keywords:||glutamate, metabotropic glutamate receptor, cerebellum, mGlu1 receptor, synaptic transmission, EPSP, METABOTROPIC GLUTAMATE RECEPTORS, PHENYLGLYCINE DERIVATIVES, ANTAGONISTS, SUBTYPES, ACID|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of)|
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of) > Wolfson Inst for Biomedical Research
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