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A randomized trial of prolonged co-trimoxazole in HIV-infected children in Africa

Bwakura-Dangarembizi, M; Kendall, L; Bakeera-Kitaka, S; Nahirya-Ntege, P; Keishanyu, R; Nathoo, K; Spyer, MJ; ... Antiretroviral Research for Watoto (ARROW) Trial Team; + view all (2014) A randomized trial of prolonged co-trimoxazole in HIV-infected children in Africa. New England Journal of Medicine , 370 (1) 41 - 53. 10.1056/NEJMoa1214901. Green open access

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Abstract

Co-trimoxazole (fixed-dose trimethoprim-sulfamethoxazole) prophylaxis administered before antiretroviral therapy (ART) reduces morbidity in children infected with the human immunodeficiency virus (HIV). We investigated whether children and adolescents receiving long-term ART in sub-Saharan Africa could discontinue co-trimoxazole.

Type: Article
Title: A randomized trial of prolonged co-trimoxazole in HIV-infected children in Africa
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1056/NEJMoa1214901
Publisher version: http://dx.doi.org/10.1056/NEJMoa1214901
Language: English
Additional information: From New England Journal of Medicine, Bwakura-Dangarembizi, M; Kendall, L; Bakeera-Kitaka, S; Nahirya-Ntege, P; Keishanyu, R; Nathoo, K; ... Antiretroviral Research for Watoto (ARROW) Trial Team,; + view all 'A randomized trial of prolonged co-trimoxazole in HIV-infected children in Africa', 370 (1) 41 - 53Author(s), Title of Article, Volume No., Page No. Copyright © 2014 Massachusetts Medical Society. Reprinted with permission.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1406348
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