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Non-invasive assessment of cardiac output at rest and during exercise by finger plethysmography

Critoph, CH; Patel, V; Mist, B; Thomas, MD; Elliott, PM; (2013) Non-invasive assessment of cardiac output at rest and during exercise by finger plethysmography. Clinical Physiology and Functional Imaging , 33 (5) pp. 338-343. 10.1111/cpf.12032.

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Abstract

Aims: We sought to determine the accuracy of finger plethysmography using pulse waveform analysis with brachial calibration for measurement of cardiac output during submaximal exercise by comparing it against an acetylene (C2H2) uptake technique. Methods: The study included 24 healthy volunteers (12 males, age 35 ± 8 years). Testing was performed on an upright cycle ergometer using an incremental protocol. Cardiac output measurements were performed at rest and during sub-maximal exercise using a single breath C2H2uptake technique and continuously using finger plethysmography with brachial calibration. Results: Valid results at rest and during sub-maximal exercise were achieved in 20 of 24 participants. Cardiac output at rest was 5·3 ± 1·1 and 5·2 ± 1·2 l min-1for finger plethysmography and C2H2,respectively, P = 0·712. Mean difference between techniques was -0·1 ± 0·5 l min-1. Cardiac output during submaximal exercise was 10·2 ± 2·3 and 10·3 ± 2·1 l min-1for finger plethysmography and C2H2,respectively, P = 0·898. Mean difference between techniques was 0·1 ± 1·5 l min-1. The overall correlation between finger plethysmography and C2H2data obtained during rest and exercise was r2= 0·872, P<0·0001. Mean rise in cardiac output during exercise was 4·9 ± 1·5 (finger plethysmography) and 5·1 ± 1·5 l min-1(C2H2), P = 0·64. Conclusion: Finger plethysmography determined cardiac output values both at rest and during sub-maximal exercise are comparable with those obtained using a single breath C2H2uptake technique. © 2013 The Authors Clinical Physiology and Functional Imaging © 2013 Scandinavian Society of Clinical Physiology and Nuclear Medicine.

Type: Article
Title: Non-invasive assessment of cardiac output at rest and during exercise by finger plethysmography
DOI: 10.1111/cpf.12032
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science > Clinical Science
URI: http://discovery.ucl.ac.uk/id/eprint/1404917
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