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Ocular inflammatory changes in established multiple sclerosis.

Graham, EM; Francis, DA; Sanders, MD; Rudge, P; (1989) Ocular inflammatory changes in established multiple sclerosis. J Neurol Neurosurg Psychiatry , 52 (12) pp. 1360-1363.

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Abstract

Fifty consecutive patients with clinically definite multiple sclerosis were studied to assess the prevalence of concomitant uveitis. Asymptomatic ocular inflammatory changes were found in nine patients (18%) and appeared to show a positive correlation with severe and progressive disease. Conversely uveitis was uncommon in the presence of established optic atrophy which suggests a negative influence on its pathogenesis. In the absence of optic atrophy inflammatory changes in the eye may be a valuable index of disease activity.

Type: Article
Title: Ocular inflammatory changes in established multiple sclerosis.
Location: England
Keywords: Adolescent, Adult, Atrophy, Chronic Disease, Eye, Female, Humans, Male, Middle Aged, Multiple Sclerosis, Ophthalmoscopy, Uveitis
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Institute of Prion Diseases
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Institute of Prion Diseases > MRC Prion Unit at UCL
URI: http://discovery.ucl.ac.uk/id/eprint/1404148
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