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Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability?

Kelly, PA; Viding, E; Wallace, GL; Schaer, M; De Brito, SA; Robustelli, B; McCrory, EJ; (2013) Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability? Biological Psychiatry , 74 (11) pp. 845-852. 10.1016/j.biopsych.2013.06.020.

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Abstract

Childhood maltreatment has been shown to significantly elevate the risk of psychiatric disorder. Previous neuroimaging studies of children exposed to maltreatment have reported atypical neural structure in several regions, including the prefrontal cortex and temporal lobes. These studies have exclusively investigated volumetric differences rather than focusing on genetically and developmentally distinct indices of brain structure.

Type: Article
Title: Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability?
DOI: 10.1016/j.biopsych.2013.06.020
Publisher version: http://dx.doi.org/10.1016/j.biopsych.2013.06.020
Language: English
Additional information: © 2013 Elsevier Inc. All rights reserved
Keywords: Child abuse, cortical thickness, local gyrification, maltreatment, psychopathology, surface area
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: http://discovery.ucl.ac.uk/id/eprint/1403245
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