UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Maternal and paternal chronic exposure to enflurane and halothane: fetal and histological changes in the rat.

Halsey, MJ; Green, CJ; Monk, SJ; Doré, C; Knight, JF; Luff, NP; (1981) Maternal and paternal chronic exposure to enflurane and halothane: fetal and histological changes in the rat. Br J Anaesth , 53 (3) pp. 203-215.

Full text not available from this repository.

Abstract

Adult male and female rats were exposed chronically to halothane 10 p.p.m., enflurane 20 p.p.m. or air for up to 64 days before mating and subsequently throughout the pregnancy of the females. The parents, progeny and, in a few cases, the subsequent generation, were studied. No abortifacient effect was seen with either agent. The groups exposed to anaesthetic had larger litters with lighter fetuses compared with their control groups. Skeletal examination did not reveal any major teratological effects for either agent. No consistent organ injury could be associated with chronic exposure to the agents under the conditions of this study.

Type: Article
Title: Maternal and paternal chronic exposure to enflurane and halothane: fetal and histological changes in the rat.
Location: England
Keywords: Abnormalities, Drug-Induced, Animals, Animals, Newborn, Birth Weight, Bone and Bones, Enflurane, Female, Fertility, Halothane, Litter Size, Male, Pregnancy, Pregnancy, Animal, Rats
URI: http://discovery.ucl.ac.uk/id/eprint/1402117
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item