Bennett, A; Foord, JS; Gaudin, O; Williams, OA; Jackman, RB; (2007) Diamond based ion-sensitive field effect transistors for cellular biosensing. In: Materials Research Society Symposium Proceedings. (pp. 221 - 227).
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The use of a chemically inert and essentially biocompatible material for cellular biosensing is an attractive idea. In this context we have studied the operation of diamond-based ion-sensitive field effect transistors (ISFETs) within solutions of varying pH, and alkali-halide concentrations, In particular, we report the use of an inexpensive diamond substrate material, often referred to as 'black' diamond. pH sensitivity was observed when devices based on hydrogen-terminated p-type surfaces where employed, provide some surface oxidation was performed prior to their use. Variation in the threshold voltage for ISFET operation of the order of 20mV/pH unit was determined. In terms of operation in potassium iodide solution, we have shown that the device is shows selective sensitivity to the iodide species, despite the equi-molar presence of both K and I species. The origin of this selectivity is discussed. © 2007 Materials Research Society.
|Title:||Diamond based ion-sensitive field effect transistors for cellular biosensing|
|UCL classification:||UCL > School of BEAMS > Faculty of Engineering Science > Electronic and Electrical Engineering|
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