Neukirch, S;
Starostin, EL;
Writhe formulas and antipodal points in plectonemic DNA configurations.
Phys. Rev. E
, 78
041912-.
10.1103/PhysRevE.78.041912.
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Abstract
The linking and writhing numbers are key quantities when characterizing the structure of a piece of supercoiled DNA. Defined as double integrals over the shape of the double-helix, these numbers are not always straightforward to compute, though a simplified formula exists. We examine the range of applicability of this widely-used simplified formula, and show that it cannot be employed for plectonemic DNA. We show that inapplicability is due to a hypothesis of Fuller theorem that is not met. The hypothesis seems to have been overlooked in many works.
| Type: | Article |
|---|---|
| Title: | Writhe formulas and antipodal points in plectonemic DNA configurations |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1103/PhysRevE.78.041912 |
| Publisher version: | http://dx.doi.org/10.1103/PhysRevE.78.041912 |
| Additional information: | 20 pages, 7 figures, 47 references |
| Keywords: | cond-mat.soft, cond-mat.soft |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/13854 |
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