Writhe formulas and antipodal points in plectonemic DNA configurations.
Phys. Rev. E
The linking and writhing numbers are key quantities when characterizing the structure of a piece of supercoiled DNA. Defined as double integrals over the shape of the double-helix, these numbers are not always straightforward to compute, though a simplified formula exists. We examine the range of applicability of this widely-used simplified formula, and show that it cannot be employed for plectonemic DNA. We show that inapplicability is due to a hypothesis of Fuller theorem that is not met. The hypothesis seems to have been overlooked in many works.
|Title:||Writhe formulas and antipodal points in plectonemic DNA configurations|
|Open access status:||An open access version is available from UCL Discovery|
|Additional information:||20 pages, 7 figures, 47 references|
|UCL classification:||UCL > School of BEAMS
UCL > School of BEAMS > Faculty of Engineering Science
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