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Non-nutritional uses of vitamin B6

Bender, DA; (1999) Non-nutritional uses of vitamin B6. British Journal of Nutrition , 81 (1) 7 - 20. 10.1017/S0007114599000082. Green open access

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Abstract

Vitamin B-6 is a water-soluble vitamin, and is readily metabolized and excreted, so it has generally been assumed to have negligible toxicity, although at very high levels of intake it can cause peripheral nerve damage. Nutritional deficiency disease is extremely rare, although a significant proportion of the population shows biochemical evidence of inadequate status, despite apparently adequate levels of intake. The vitamin has been used to treat a wide variety of conditions, which may or may not be related to inadequate intake. In some conditions use of vitamin B-6 supplements has been purely empirical; in other conditions there is a reasonable physiological or metabolic mechanism to explain why supplements of the vitamin many times greater than average requirements may have therapeutic uses. However, even in such conditions there is little evidence of efficacy from properly conducted controlled trials.

Type: Article
Title: Non-nutritional uses of vitamin B6
Open access status: An open access version is available from UCL Discovery
DOI: 10.1017/S0007114599000082
Publisher version: https://www.cambridge.org/core/journals/british-jo...
Language: English
Additional information: © Nutrition Society 1999
Keywords: vitamin B-6, carpal tunnel syndrome, glucose tolerance, premenstrual syndrome, CARPAL-TUNNEL SYNDROME, SYSTOLIC BLOOD-PRESSURE, DOUBLE-BLIND, PREMENSTRUAL-SYNDROME, PYRIDOXINE VITAMIN-B6, TRYPTOPHAN-METABOLISM, MUSCLE PHOSPHORYLASE, INDUCED HYPERTENSION, SENSORY NEUROPATHY, DIABETES-MELLITUS
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology
URI: http://discovery.ucl.ac.uk/id/eprint/138216
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