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Cushing's syndrome, tryptophan and depression

Kelly, WF; Checkley, SA; Bender, DA; (1980) Cushing's syndrome, tryptophan and depression. The British Journal of Psychiatry , 136 pp. 125-32.

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Abstract

Fifteen patients with active Cushing's syndrome have been compared with 15 other patients who had been treated successfully for Cushing's syndrome and with 13 patients with other pituitary tumours. Depression was the main psychiatric diagnosis made by the CATEGO programme after Present State Examinations. Patients with active Cushing's syndrome were significantly more depressed (Hamilton Rating Scores), than were the other patients. Compared with the control patients, those with active Cushing's syndrome had slightly lower plasma concentrations of total tryptophan, though the concentrations of freely diffusible tryptophan were not significantly changed.

Type: Article
Title: Cushing's syndrome, tryptophan and depression
Additional information: 0007-1250 (Print)Comparative StudyJournal Article
Keywords: Adolescent, Adult, Aged, Cushing Syndrome, blood, complications, psychology, surgery, Depression, etiology, Female, Humans, Male, Middle Aged, Pituitary Neoplasms, Tryptophan
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology
URI: http://discovery.ucl.ac.uk/id/eprint/137496
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