UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Pulmonary thromboendarterectomy in adolescents and young adults.

Johnson, JN; Driscoll, DJ; McGregor, CGA; (2010) Pulmonary thromboendarterectomy in adolescents and young adults. Pediatr Pulmonol , 45 (6) pp. 614-618. 10.1002/ppul.21231.

Full text not available from this repository.

Abstract

OBJECTIVES: Chronic thromboembolic pulmonary hypertension (CTEPH) occurs in patients with recurrent or chronic pulmonary embolism, and is a rare but potentially devastating disease in adolescents and young adults. Pulmonary thromboendarterectomy (PTE) is an important curative therapy for patients with CTEPH. The importance of this treatment may be under-appreciated and under-utilized in adolescents and young adults. STUDY DESIGN: We performed a chart review of all patients <24 years of age who had PTE performed for CTEPH at our institution from 2003-2009 (seven patients, average age 20.2 +/- 2.5 years, range 17-23 years, average BMI 34 +/- 12 kg/m(2)). All patients had their operations performed by a single surgeon. RESULTS: There were no deaths. Three of the seven patients were incorrectly diagnosed prior to the diagnosis of CTEPH. Right ventricular systolic pressure decreased from 61.3 +/- 19 mmHg pre-operatively to 31.8 +/- 5 mmHg post-operatively (P = 0.008). All patients reported symptomatic relief, and no patient has had recurrence of CTEPH. CONCLUSION: Although rare in the young patient, recurrent pulmonary emboli can have devastating consequences. The potentially lethal implications of CTEPH may be under-appreciated in adolescents and young adults. When indicated, PTE is a definitive, curative procedure with low morbidity and mortality.

Type: Article
Title: Pulmonary thromboendarterectomy in adolescents and young adults.
Location: United States
DOI: 10.1002/ppul.21231
Keywords: Adolescent, Endarterectomy, Female, Humans, Hypertension, Pulmonary, Lung, Male, Pulmonary Artery, Pulmonary Embolism, Treatment Outcome, Young Adult
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science > Pre-clinical and Fundamental Science
URI: http://discovery.ucl.ac.uk/id/eprint/1373724
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item