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Synthesis of ethyl 1-azabicyclo[2.2.1]hept-4-yl carboxylate

Orlek, BS; Wadsworth, H; Wyman, P; King, FD; (1991) Synthesis of ethyl 1-azabicyclo[2.2.1]hept-4-yl carboxylate. Tetrahedron Letters , 32 (9) 1245 - 1246. 10.1016/S0040-4039(00)92056-2.

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The dipolar cycloaddition reaction of α-methylene butyrolactone and N-benzyl azomethine ylid (5) affords the spirolactone (2) which rearranges to give ethyl 1-zabicyclo[2.2.1]hept-4-yl carboxylate (1) in excellent overall yield. © 1991.

Title:Synthesis of ethyl 1-azabicyclo[2.2.1]hept-4-yl carboxylate
UCL classification:UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Chemistry

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