Synthesis of ethyl 1-azabicyclo[2.2.1]hept-4-yl carboxylate.
The dipolar cycloaddition reaction of α-methylene butyrolactone and N-benzyl azomethine ylid (5) affords the spirolactone (2) which rearranges to give ethyl 1-zabicyclo[2.2.1]hept-4-yl carboxylate (1) in excellent overall yield. © 1991.
|Title:||Synthesis of ethyl 1-azabicyclo[2.2.1]hept-4-yl carboxylate|
|UCL classification:||UCL > School of BEAMS
UCL > School of BEAMS > Faculty of Maths and Physical Sciences
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