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Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration

Worth, AJJ; Metelo, J; Bouma, G; Moulding, D; Fritzsche, M; Vernay, B; Charras, G; ... Burns, SO; + view all (2013) Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration. BLOOD , 121 (1) pp. 72-84. 10.1182/blood-2012-01-403857.

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Type: Article
Title: Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration
DOI: 10.1182/blood-2012-01-403857
Keywords: Science & Technology, Life Sciences & Biomedicine, Hematology, WISKOTT-ALDRICH-SYNDROME, SYNDROME PROTEIN WASP, N-WASP, INTERACTING PROTEIN, ARP2/3 COMPLEX, ACTIVATING MUTATIONS, FILOPODIUM FORMATION, WASP/SCAR PROTEINS, GENE-MUTATIONS, WIP COMPLEX
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health > ICH Development Bio and Cancer Prog
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health > ICH Infect, Imm, Infla. and Physio Med
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > London Centre for Nanotechnology
URI: http://discovery.ucl.ac.uk/id/eprint/1372508
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