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Mass Spectrometry Reveals That the Antibiotic Simocyclinone D8 Binds to DNA Gyrase in a "Bent-Over" Conformation: Evidence of Positive Cooperativity in Binding

Edwards, MJ; Williams, MA; Maxwell, A; McKay, AR; (2011) Mass Spectrometry Reveals That the Antibiotic Simocyclinone D8 Binds to DNA Gyrase in a "Bent-Over" Conformation: Evidence of Positive Cooperativity in Binding. BIOCHEMISTRY , 50 (17) pp. 3432-3440. 10.1021/bi101691k.

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Type: Article
Title: Mass Spectrometry Reveals That the Antibiotic Simocyclinone D8 Binds to DNA Gyrase in a "Bent-Over" Conformation: Evidence of Positive Cooperativity in Binding
DOI: 10.1021/bi101691k
Keywords: Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, BIOCHEMISTRY & MOLECULAR BIOLOGY, BREAKAGE-REUNION DOMAIN, PROTEIN COMPLEXES, STRUCTURE ELUCIDATION, INHIBITORS, TOPOISOMERASES, TU-6040, BIOLOGY
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of) > Structural and Molecular Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1371348
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