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The identification of novel PLC-gamma inhibitors using virtual high throughput screening

Reynisson, J; Court, W; O'Neill, C; Day, J; Patterson, L; McDonald, E; Workman, P; ... Eccles, SA; + view all (2009) The identification of novel PLC-gamma inhibitors using virtual high throughput screening. BIOORGANIC & MEDICINAL CHEMISTRY , 17 (8) pp. 3169-3176. 10.1016/j.bmc.2009.02.049.

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Type: Article
Title: The identification of novel PLC-gamma inhibitors using virtual high throughput screening
DOI: 10.1016/j.bmc.2009.02.049
Keywords: Science & Technology, Life Sciences & Biomedicine, Physical Sciences, Biochemistry & Molecular Biology, Chemistry, Medicinal, Chemistry, Organic, Pharmacology & Pharmacy, Chemistry, Virtual screening, PLC-protein, Oncology, Docking, Drug discovery, PHOSPHOLIPASE-C-GAMMA, SMALL-MOLECULE INHIBITORS, COMPOUND LIBRARIES, TUMOR PROGRESSION, SCORING FUNCTIONS, BINDING-AFFINITY, ESCHERICHIA-COLI, DRUG SOLUBILITY, CELL MOTILITY, DOCKING
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1365216
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