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A Novel N-ethyl-N-nitrosourea-Induced Mutation in Phospholipase C gamma 2 Causes Inflammatory Arthritis, Metabolic Defects, and Male Infertility In Vitro in a Murine Model

Abe, K; Fuchs, H; Boersma, A; Hans, W; Yu, P; Kalaydjiev, S; Klaften, M; ... de Angelis, MH; + view all (2011) A Novel N-ethyl-N-nitrosourea-Induced Mutation in Phospholipase C gamma 2 Causes Inflammatory Arthritis, Metabolic Defects, and Male Infertility In Vitro in a Murine Model. ARTHRITIS AND RHEUMATISM , 63 (5) pp. 1301-1311. 10.1002/art.30280.

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Type: Article
Title: A Novel N-ethyl-N-nitrosourea-Induced Mutation in Phospholipase C gamma 2 Causes Inflammatory Arthritis, Metabolic Defects, and Male Infertility In Vitro in a Murine Model
DOI: 10.1002/art.30280
Keywords: Science & Technology, Life Sciences & Biomedicine, Rheumatology, RHEUMATOLOGY, PLECKSTRIN HOMOLOGY DOMAIN, ENU-MOUSE-MUTAGENESIS, B-CELL DEVELOPMENT, PHENOTYPIC CHARACTERIZATION, TYROSINE KINASE, MUTANT MICE, GENOME-WIDE, ALI18, PLC-GAMMA-2, INVOLVEMENT
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of) > Structural and Molecular Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1365214
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