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A Bayesian approach to phylogeographic clustering.

Manolopoulou, I; Legarreta, L; Emerson, BC; Brooks, S; Tavaré, S; (2011) A Bayesian approach to phylogeographic clustering. Interface Focus , 1 (6) pp. 909-921. 10.1098/rsfs.2011.0054.

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Abstract

Phylogeographic methods have attracted a lot of attention in recent years, stressing the need to provide a solid statistical framework for many existing methodologies so as to draw statistically reliable inferences. Here, we take a flexible fully Bayesian approach by reducing the problem to a clustering framework, whereby the population distribution can be explained by a set of migrations, forming geographically stable population clusters. These clusters are such that they are consistent with a fixed number of migrations on the corresponding (unknown) subdivided coalescent tree. Our methods rely upon a clustered population distribution, and allow for inclusion of various covariates (such as phenotype or climate information) at little additional computational cost. We illustrate our methods with an example from weevil mitochondrial DNA sequences from the Iberian peninsula.

Type: Article
Title: A Bayesian approach to phylogeographic clustering.
Location: England
DOI: 10.1098/rsfs.2011.0054
Keywords: Markov chain Monte Carlo, coalescent, island model, migration, reversible jump, subdivided population
UCL classification: UCL > School of BEAMS
UCL > School of BEAMS > Faculty of Maths and Physical Sciences
URI: http://discovery.ucl.ac.uk/id/eprint/1361666
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