UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Functional polymorphism (5-HTTLPR) in the serotonin transporter gene is associated with subjective well-being: evidence from a US nationally representative sample.

De Neve, JE; (2011) Functional polymorphism (5-HTTLPR) in the serotonin transporter gene is associated with subjective well-being: evidence from a US nationally representative sample. J Hum Genet , 56 (6) pp. 456-459. 10.1038/jhg.2011.39.

Full text not available from this repository.

Abstract

Variation in the promotor region of the serotonin transporter gene (5-HTTLPR) is a promising candidate for better understanding individual heterogeneity in subjective well-being or happiness, as measured by life satisfaction. This functional polymorphism has previously been associated with mental health and selective processing of positive and negative emotional stimuli. A case-control association study on a representative sample of Americans (N=2574) finds that individuals with the transcriptionally more efficient version of the serotonin transporter gene, report significantly higher levels of life satisfaction (P=0.01). This new finding may help explain the important genetic component of the individual baseline levels of happiness.

Type: Article
Title: Functional polymorphism (5-HTTLPR) in the serotonin transporter gene is associated with subjective well-being: evidence from a US nationally representative sample.
Location: England
DOI: 10.1038/jhg.2011.39
Keywords: Adolescent, Adult, Alleles, Case-Control Studies, Gene Frequency, Genotype, Humans, Personal Satisfaction, Polymorphism, Genetic, Serotonin Plasma Membrane Transport Proteins, United States, Young Adult
UCL classification: UCL > School of Arts and Social Sciences > Faculty of Social and Historical Sciences
UCL > School of Arts and Social Sciences > Faculty of Social and Historical Sciences > Political Science
URI: http://discovery.ucl.ac.uk/id/eprint/1359517
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item