Wunderlich, K and Smittenaar, P and Dolan, RJ (2012) Dopamine enhances model-based over model-free choice behavior. Neuron , 75 (3) 418 - 424. 10.1016/j.neuron.2012.03.042.
Decision making is often considered to arise out of contributions from a model-free habitual system and a model-based goal-directed system. Here, we investigated the effect of a dopamine manipulation on the degree to which either system contributes to instrumental behavior in a two-stage Markov decision task, which has been shown to discriminate model-free from model-based control. We found increased dopamine levels promote model-based over model-free choice.
|Title:||Dopamine enhances model-based over model-free choice behavior.|
|Open access status:||An open access publication|
|Additional information:||PMCID: PMC3417237|
|Keywords:||Benserazide, Brain, Choice Behavior, Dopamine, Dopamine Agents, Double-Blind Method, Humans, Male, Markov Chains, Models, Neurological, Models, Theoretical, Young Adult|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > Imaging Neuroscience|
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