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Identification in human urine of delta 9-tetrahydrocannabinol-11-oic acid glucuronide: a tetrahydrocannabinol metabolite.

Williams, PL; Moffat, AC; (1980) Identification in human urine of delta 9-tetrahydrocannabinol-11-oic acid glucuronide: a tetrahydrocannabinol metabolite. J Pharm Pharmacol , 32 (7) pp. 445-448.

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Abstract

A delta 9-THC metabolite has been identified in human urine as an ester linked glucuronide of delta 9-THC-11-oic acid. Its identity was established by a comparison of mass spectra from the metabolite extracted from human urine and synthetically prepared material. delta 9-THC-11-oic acid glucuronide was found to be responsible for the major part of RIA cross-reactivity in urine with the Guildhay cannabinoid antiserum used in this study.

Type: Article
Title: Identification in human urine of delta 9-tetrahydrocannabinol-11-oic acid glucuronide: a tetrahydrocannabinol metabolite.
Location: England
Keywords: Animals, Chromatography, High Pressure Liquid, Dronabinol, Glucuronates, Glucuronidase, Humans, Hydrolysis, Mass Spectrometry, Rabbits, Radioimmunoassay
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
URI: http://discovery.ucl.ac.uk/id/eprint/1353002
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