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In vivo evaluation of pH-sensitive polymeric microparticles for site specific drug delivery to the small intestine and colon

Kendall, RA; Murdan, S; Basit, AW; (2006) In vivo evaluation of pH-sensitive polymeric microparticles for site specific drug delivery to the small intestine and colon. Presented at: 33rd International Symposium of the Controlled Release Society, Vienna, Austria. Green open access

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Abstract

A novel emulsification/solvent evaporation process was developed to formulate prednisolone-loaded Eudragit L and S microparticles as drug delivery vehicles to target different regions of the gastrointestinal tract. Microparticles were characterised in vitro and in vivo. This is the first report of drug absorption form orally administered Eudragit L and S microparticles.

Type: Conference item (UNSPECIFIED)
Title: In vivo evaluation of pH-sensitive polymeric microparticles for site specific drug delivery to the small intestine and colon
Event: 33rd International Symposium of the Controlled Release Society
Location: Vienna, Austria
Dates: 22/07/2006 26/07/2006
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Conference abstract
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics
URI: https://discovery.ucl.ac.uk/id/eprint/1351102
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