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A method for three-dimensional time-resolved optical tomography

Arridge, SR; Hebden, JC; Schwinger, M; Schmidt, FEW; Fry, ME; Hillman, EMC; ... Delpy, DT; + view all (2000) A method for three-dimensional time-resolved optical tomography. INT J IMAG SYST TECH , 11 (1) 2 - 11.

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Abstract

We present an overview of time-resolved optical tomography together with the hardware and software methods that we have developed for a clinical instrument that implements this modality. The hardware is based on a multichannel photon-counting technique that records the histograms of photons time-of-flight through highly scattering and attenuating media. The software is based on a finite element model that is iteratively updated in order to minimize the difference between measured and modeled data. We have presented a first experimental reconstruction of a three-dimensional (3D) distribution of variable absorption and scattering coefficient, together with an ideal simulation of the same case. (C) 2000 John Wiley & Sons, Inc.

Type:Article
Title:A method for three-dimensional time-resolved optical tomography
Keywords:FINITE-ELEMENT-METHOD, MEASUREMENT DENSITY-FUNCTIONS, IMAGE-RECONSTRUCTION, SCATTERING MEDIA, ABSORPTION-COEFFICIENTS, OF-FLIGHT, TISSUE, LIGHT, DIFFUSION, APPROXIMATION
UCL classification:UCL > School of BEAMS > Faculty of Engineering Science > Computer Science
UCL > School of BEAMS > Faculty of Engineering Science > Medical Physics and Bioengineering

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