Lynch, NE and Stevenson, NJ and Livingstone, V and Murphy, BP and Rennie, JM and Boylan, GB (2012) The temporal evolution of electrographic seizure burden in neonatal hypoxic ischemic encephalopathy. Epilepsia , 53 (3) 549 - 557. 10.1111/j.1528-1167.2011.03401.x.
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Hypoxic ischemic encephalopathy (HIE) accounts for 60% of all neonatal seizures. There is emerging evidence that seizures cause additional injury to the developing brain that has sustained hypoxic ischemic injury. Temporal evolution of clinical seizure burden in HIE has been characterized, with maximum clinical seizure burden (the period of maximum seizure activity) being observed between 12 and 24 h of age. The purpose of our study was to investigate the distribution of electrographic seizure burden (the accumulated duration of seizures over a defined time period), following the initial hypoxic ischemic insult.
|Title:||The temporal evolution of electrographic seizure burden in neonatal hypoxic ischemic encephalopathy.|
|Keywords:||Asphyxia Neonatorum, Brain Waves, Disease Progression, Electroencephalography, Epilepsy, Female, Humans, Hypoxia-Ischemia, Brain, Infant, Newborn, Male, Retrospective Studies, Time Factors|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Women's Health > Maternal and Fetal Medicine|
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