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The development and validation of the King's Brief Interstitial Lung Disease (K-BILD) health status questionnaire.

Patel, AS; Siegert, RJ; Brignall, K; Gordon, P; Steer, S; Desai, SR; Maher, TM; (2012) The development and validation of the King's Brief Interstitial Lung Disease (K-BILD) health status questionnaire. Thorax , 67 (9) pp. 804-810. 10.1136/thoraxjnl-2012-201581.

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Abstract

RATIONALE: Health status is impaired in patients with interstitial lung disease (ILD). There is a paucity of tools that assess health status in ILD. The objective of this study was to develop and validate the King's Brief Interstitial Lung Disease questionnaire (K-BILD), a new health status measure for patients with ILD. METHODS: Patients with ILD were recruited from outpatient clinics. The development of the questionnaire consisted of three phases: item generation; item reduction, allocation to domains by factor analysis, Rasch analysis to create unidimensional scales and validation; and repeatability testing. RESULTS: 173 patients with ILD (49 with idiopathic pulmonary fibrosis) completed a preliminary 71-item questionnaire. 56 items were removed due to redundancy, low factor loadings or poor fit to the Rasch model. The final version of the K-BILD questionnaire consisted of 15 items and three domains (breathlessness and activities, chest symptoms and psychological). Internal consistency assessed with Cronbach's α coefficient was 0.94 for the K-BILD total score. Concurrent validity of the K-BILD questionnaire was high compared with St George's Respiratory Questionnaire (r=0.90) and moderate with lung function (vital capacity, r=0.50). The K-BILD questionnaire was repeatable over 2 weeks (n=44), with intraclass correlation coefficients for domains and total score 0.86-0.94. The K-BILD construct validity for patients with idiopathic pulmonary fibrosis was similar to that of other ILDs. CONCLUSION: The K-BILD questionnaire is a brief, valid, self-completed health status measure for ILD. It could be used in the clinic to assess ILD from the patients' perspective.

Type: Article
Title: The development and validation of the King's Brief Interstitial Lung Disease (K-BILD) health status questionnaire.
Location: England
DOI: 10.1136/thoraxjnl-2012-201581
Keywords: Chi-Square Distribution, Female, Health Status, Humans, London, Lung Diseases, Interstitial, Male, Predictive Value of Tests, Severity of Illness Index, Surveys and Questionnaires
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)
URI: http://discovery.ucl.ac.uk/id/eprint/1346672
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