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Diffuse optical cortical mapping using the boundary element method.

Elisee, J; Gibson, A; Arridge, S; (2011) Diffuse optical cortical mapping using the boundary element method. Biomed Opt Express , 2 (3) 568 - 578. 10.1364/BOE.2.000568. Gold open access

Abstract

Cortical mapping, also called optical topography is a new medical imaging modality which allows the non-invasive investigation of the outer layers of the cortex. This technique is challenging and the geometry of the subject is very often over-simplified. We aim here to localize activated regions of an anatomically accurate brain. A Boundary Element Method is used for the forward model. The reconstruction of perturbations in the absorption coefficient is demonstrated in a geometrically realistic simulation and in vivo. These results show that diffuse optical imaging of the head can provide reliable activity maps when anatomical data is available.

Type:Article
Title:Diffuse optical cortical mapping using the boundary element method.
Location:United States
Open access status:An open access publication
DOI:10.1364/BOE.2.000568
Language:English
Keywords:(110.0113) Imaging through turbid media, (110.3200) Inverse scattering, (170.3010) Image reconstruction techniques
UCL classification:UCL > School of BEAMS > Faculty of Engineering Science > Computer Science
UCL > School of BEAMS > Faculty of Engineering Science > Medical Physics and Bioengineering

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