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Trends in depression and antidepressant prescribing in children and adolescents: a cohort study in The Health Improvement Network (THIN).

Wijlaars, LP; Nazareth, I; Petersen, I; (2012) Trends in depression and antidepressant prescribing in children and adolescents: a cohort study in The Health Improvement Network (THIN). PLoS One , 7 (3) , Article e33181. 10.1371/journal.pone.0033181. Green open access

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Abstract

In 2003, the Committee on Safety of Medicines (CSM) advised against treatment with selective serotonin reuptake inhibitors (SSRIs) other than fluoxetine in children, due to a possible increased risk of suicidal behaviour. This study examined the effects of this safety warning on general practitioners' depression diagnosing and prescription behaviour in children.

Type: Article
Title: Trends in depression and antidepressant prescribing in children and adolescents: a cohort study in The Health Improvement Network (THIN).
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pone.0033181
Publisher version: http://dx.doi.org/10.1371/journal.pone.0033181
Language: English
Additional information: © 2012 Wijlaars et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PMCID: PMC3302807 LPW received support from the National Institute of Health Research English National School for Primary Care Research (http://www.nspcr.ac.uk/) for the submitted work. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Keywords: Adolescent, Age Factors, Antidepressive Agents, Child, Cohort Studies, Depression, Drug Utilization, England, Female, Humans, Male, Serotonin Uptake Inhibitors, Sex Factors
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Primary Care and Population Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1346265
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