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Risks of fracture of Bjork-Shiley 60 degrees convexo-concave prosthetic heart valves: Long-term cohort follow up in the UK, Netherlands and USA

Blot, WJ; Omar, RZ; Kallewaard, M; Morton, LS; Fryzek, JP; Ibrahim, MA; ... van der Graaf, Y; + view all (2001) Risks of fracture of Bjork-Shiley 60 degrees convexo-concave prosthetic heart valves: Long-term cohort follow up in the UK, Netherlands and USA. J HEART VALVE DIS , 10 (2) 202 - 209.

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Abstract

Background and aim of the study: Approximately 82,000 Bjork-Shiley convexo-concave (BSCC) 60 degrees prosthetic heart valves were implanted in patients worldwide between 1979 and 1986. Outlet strut fractures (OSF) of some of the valves were first reported shortly after their introduction. Here, the determinants of OSF are examined, and the between-country variation and long-term risk are assessed.Methods: Cohorts of patients in the UK, Netherlands and USA with 15,770 BSCC 60 degrees heart valves were followed up to 18 years for the occurrence of OSF.Results: Crude rates of OSF were highest in the UK (0.18% per year), intermediate in the Netherlands (0.13%), and lowest in the USA (0.06%), although risk factor adjustment reduced the inter-country differences. Furthermore, in the UK and Netherlands, OSF rates (particularly for mitral valves) declined with time since implantation, and between-country differences were considerably diminished 10 or more years post implantation. The risk of OSF decreased steadily with advancing patient age. Fracture rates were lower among women than men, and also varied significantly with valve size and position and OSF status of other valves in the same shoporder.Conclusion: This long-term follow up of BSCC 60 degrees heart valve patients indicates that risk factors for valve fracture are generally similar in the UK, Netherlands and USA. It also identifies a strong association between fracture risk and age, newly reveals gender-related differences, and shows that the risk of valve fracture persisted, albeit at a reduced rate, into the 1990s.

Type:Article
Title:Risks of fracture of Bjork-Shiley 60 degrees convexo-concave prosthetic heart valves: Long-term cohort follow up in the UK, Netherlands and USA
Keywords:OUTLET STRUT FRACTURE, MECHANICAL FAILURE
UCL classification:UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Statistical Science

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