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Diagnostic modelling of multi-parametric MRI as a radiological tool to predict transition zone prostate cancer

Dikaios, N; Fujiwara, T; Abd Alazeez, M; Atkinson, D; Punwani, S; (2012) Diagnostic modelling of multi-parametric MRI as a radiological tool to predict transition zone prostate cancer. In: (Proceedings) ISMRM 2012. (pp. 547 - ?).

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Abstract

Multi-parametric MRI has a reported sensitivity of 73% and specificity of 89% for detection of tumour within the peripheral zone of the prostate. However, benign prostatic hypertrophy as commonly found in the transition zone produces signal changes that make the radiologists detection of anterior gland tumour more difficult. Our study derived a predictive model for classification of suspected sites of anterior gland disease based on clinical (age, PSA, gland volume, PSA density), quantitative MRI parameters (ADC, contrast enhanced, T2 image signal) and textural features of MR images (entropy, contrast, co-occurance); and compared the performance of this model for detection of tumour against a consensus radiologist opinion.

Type:Proceedings paper
Title:Diagnostic modelling of multi-parametric MRI as a radiological tool to predict transition zone prostate cancer
Event:ISMRM 2012
Location:Melbourne, Australia
Dates:2012-05-07 - 2012-05-12
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)

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