Menys, A and Odille, F and Punwani, S and Novelli, M and Rodriguez-Justo, M and Halligan, S and Atkinson, D and Taylor, S (2012) MRI derived small bowel motility as a marker of Crohn’s disease activity. In: (Proceedings) ISMRM 2012. (pp. 1274 - ?).
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Optimal medical management of Crohn’s disease (CD) relies on accurate identification of patients with acute inflammation. Currently a number of anatomical features seen on MR enterography have been shown to correlate closely with disease activity. Abnormal intestinal motility has been described in CD and may also be a marker for disease activity. We explored quantitatively the relationship between CD activity and intestinal motility assessed using MRI (n=23) against a histopathological standard of reference and validated anatomical MRI markers of activity. We found significant relationships between motility and both end points suggesting motility as a biomarker for inflammatory activity.
|Title:||MRI derived small bowel motility as a marker of Crohn’s disease activity|
|Dates:||2012-05-07 - 2012-05-12|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)|
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