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MRI derived small bowel motility as a marker of Crohn’s disease activity

Menys, A; Odille, F; Punwani, S; Novelli, M; Rodriguez-Justo, M; Halligan, S; Atkinson, D; (2012) MRI derived small bowel motility as a marker of Crohn’s disease activity. In: (Proceedings) ISMRM 2012. (pp. 1274 - ?).

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Abstract

Optimal medical management of Crohn’s disease (CD) relies on accurate identification of patients with acute inflammation. Currently a number of anatomical features seen on MR enterography have been shown to correlate closely with disease activity. Abnormal intestinal motility has been described in CD and may also be a marker for disease activity. We explored quantitatively the relationship between CD activity and intestinal motility assessed using MRI (n=23) against a histopathological standard of reference and validated anatomical MRI markers of activity. We found significant relationships between motility and both end points suggesting motility as a biomarker for inflammatory activity.

Type: Proceedings paper
Title: MRI derived small bowel motility as a marker of Crohn’s disease activity
Event: ISMRM 2012
Location: Melbourne, Australia
Dates: 2012-05-07 - 2012-05-12
UCL classification: UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)
URI: http://discovery.ucl.ac.uk/id/eprint/1345032
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