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The involvement of calcium in the stimulation of respiration in isolated rat hepatocytes by adrenergic agonists and glucagon.

Crompton, M; Goldstone, TP; (1986) The involvement of calcium in the stimulation of respiration in isolated rat hepatocytes by adrenergic agonists and glucagon. FEBS Lett , 204 (2) pp. 198-202.

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Abstract

The effects of adrenergic agonists and glucagon on respiration and cytosolic free Ca2+, measured with quin2, in female rat hepatocytes have been compared. In the presence of lactate, all three agonists caused a permanent stimulation of respiration. However, unlike phenylephrine, glucagon induced only a transient increase in cytosolic free Ca2+, and isoprenaline caused no detectable change. Mechanisms other than Ca2+ for respiratory stimulation by cAMP-linked agonists in liver are indicated.

Type: Article
Title: The involvement of calcium in the stimulation of respiration in isolated rat hepatocytes by adrenergic agonists and glucagon.
Location: NETHERLANDS
Keywords: Aminoquinolines, Animals, Biological Transport, Calcium, Female, Fluorescent Dyes, Glucagon, Isoproterenol, Liver, Mitochondria, Liver, Oxygen Consumption, Phenylephrine, Rats, Rats, Inbred Strains
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of)
URI: http://discovery.ucl.ac.uk/id/eprint/1344267
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