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Respiration-dependent efflux of magnesium ions from heart mitochondria.

Crompton, M; Capano, M; Carafoli, E; (1976) Respiration-dependent efflux of magnesium ions from heart mitochondria. Biochem J , 154 (3) 735 - 742.

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Abstract

Energy-linked respiration causes a net movement of Mg2+ between rat heart mitochondria and the ambient medium. When the extramitochondrial concontration of Mg2+ is less that about 2.5 mM the net movement of Mg2+ constitutes an efflux, whereas a net influx of Mg2+ occurs when the external concentration of Mg2+ is greater than this. Both the efflux and the influx are induced to only a very small degree by externally added ATP. Evidence suggests that Pi may be required for the respiration-induced efflux of Mg2+.

Type:Article
Title:Respiration-dependent efflux of magnesium ions from heart mitochondria.
Location:ENGLAND
Language:English
Keywords:Adenosine Diphosphate, Adenosine Triphosphate, Animals, Calcium, Electron Transport, In Vitro Techniques, Ketoglutaric Acids, Magnesium, Mitochondria, Muscle, Myocardium, Oligomycins, Oxygen Consumption, Phosphates, Rats, Rotenone
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of)

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