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Cellular heterogeneity during vertebrate skeletal muscle development.

Biressi, S; Molinaro, M; Cossu, G; (2007) Cellular heterogeneity during vertebrate skeletal muscle development. Dev Biol , 308 (2) pp. 281-293. 10.1016/j.ydbio.2007.06.006.

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Abstract

Although skeletal muscles appear superficially alike at different anatomical locations, in reality there is considerably more diversity than previously anticipated. Heterogeneity is not only restricted to completely developed fibers, but is clearly apparent during development at the molecular, cellular and anatomical level. Multiple waves of muscle precursors with different features appear before birth and contribute to muscular diversification. Recent cell lineage and gene expression studies have expanded our knowledge on how skeletal muscle is formed and how its heterogeneity is generated. This review will present a comprehensive view of relevant findings in this field.

Type: Article
Title: Cellular heterogeneity during vertebrate skeletal muscle development.
Location: United States
DOI: 10.1016/j.ydbio.2007.06.006
Keywords: Animals, Biological Evolution, Body Patterning, Cell Differentiation, Humans, Mice, Models, Biological, Muscle Development, Muscle Fibers, Skeletal, Muscle, Skeletal, Myoblasts, Skeletal, Myogenic Regulatory Factors, Phenotype
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1342585
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