CD44 isoform expression on colonic epithelium mediates lamina propria lymphocyte adhesion and is controlled by Th1 and Th2 cytokines.
Eur J Gastroenterol Hepatol
CD44v6 and CD44v3 are expressed on the surface of colonic epithelial cells in ulcerative colitis to a much greater extent than in Crohn's disease. We investigated mediators that induce CD44v6 and CD44v3 expression on colonic epithelium and the potential role of CD44 in mediating leucocyte-epithelial adhesion.
|Title:||CD44 isoform expression on colonic epithelium mediates lamina propria lymphocyte adhesion and is controlled by Th1 and Th2 cytokines.|
|Keywords:||Antigens, CD44, Basement Membrane, Cell Adhesion, Colitis, Ulcerative, Colon, Cytokines, Glycoproteins, HT29 Cells, Humans, Inflammatory Bowel Diseases, Interleukin-13, Interleukin-4, Intestinal Mucosa, Th1 Cells, Th2 Cells, Up-Regulation|
|UCL classification:||UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)
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