Donnan, PT; McLernon, D; Steinke, D; Ryder, S; Roderick, P; Sullivan, FM; ... Dillon, JF; + view all Donnan, PT; McLernon, D; Steinke, D; Ryder, S; Roderick, P; Sullivan, FM; Rosenberg, W; Dillon, JF; - view fewer (2007) Development of a decision support tool to facilitate primary care management of patients with abnormal liver function tests without clinically apparent liver disease [HTA03/38/02]. Abnormal Liver Function Investigations Evaluation (ALFIE). BMC Health Services Research , 7 , Article 54. 10.1186/1472-6963-7-54.
Liver function tests (LFTs) are routinely performed in primary care, and are often the gateway to further invasive and/or expensive investigations. Little is known of the consequences in people with an initial abnormal liver function (ALF) test in primary care and with no obvious liver disease. Further investigations may be dangerous for the patient and expensive for Health Services. The aims of this study are to determine the natural history of abnormalities in LFTs before overt liver disease presents in the population and identify those who require minimal further investigations with the potential for reduction in NHS costs.
|Title:||Development of a decision support tool to facilitate primary care management of patients with abnormal liver function tests without clinically apparent liver disease [HTA03/38/02]. Abnormal Liver Function Investigations Evaluation (ALFIE)|
|Open access status:||An open access version is available from UCL Discovery|
|Additional information:||© 2007 Donnan et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. PMCID: PMC1868021|
|Keywords:||Adolescent, Adult, Aged, Cost-Benefit Analysis, Decision Support Techniques, Female, Humans, Incidence, Liver Diseases, Liver Function Tests, Male, Medical Records Systems, Computerized, Reference Values, Registries, Retrospective Studies, Scotland|
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