Trépo, E and Potthoff, A and Pradat, P and Bakshi, R and Young, B and Lagier, R and Moreno, C and Verset, L and Cross, R and Degré, D and Lemmers, A and Gustot, T and Berthillon, P and Rosenberg, W and Trépo, C and Sninsky, J and Adler, M and Wedemeyer, H (2011) Role of a cirrhosis risk score for the early prediction of fibrosis progression in hepatitis C patients with minimal liver disease. J Hepatol , 55 (1) 38 - 44. 10.1016/j.jhep.2010.10.018.
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Fibrosis progression in patients with chronic hepatitis C (CHC) is highly variable. A Cirrhosis Risk Score (CRS) based on seven genetic variants has been recently developed for identifying patients at risk for cirrhosis. The objective of this study was to assess the role of the CRS for the early prediction of fibrosis progression in CHC patients with mild liver fibrosis. In addition, we evaluated the potential benefit, for prediction accuracy, of a recently described non-invasive fibrosis staging assay, the Enhanced Liver Fibrosis (ELF) test.
|Title:||Role of a cirrhosis risk score for the early prediction of fibrosis progression in hepatitis C patients with minimal liver disease.|
|Keywords:||Cohort Studies, Disease Progression, Female, Genetic Variation, Hepatitis C, Chronic, Humans, Liver Cirrhosis, Male, Middle Aged, Multivariate Analysis, Polymorphism, Single Nucleotide, Retrospective Studies, Risk Factors|
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