Rosenberg, W and Ireland, A and Jewell, DP (1990) High-dose methylprednisolone in the treatment of active ulcerative colitis. J Clin Gastroenterol , 12 (1) 40 - 41.
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Twenty patients with severe active ulcerative colitis were entered into a pilot study to test the efficacy of pulsed high-dose methylprednisolone in inducing remission. Of 20 patients, 12 improved, but 8 of 20 patients (40%) who did not went for urgent colectomy. The group proceeding to surgery tended to have more extensive disease. These results contrast unfavorably with historical control data from this unit.
|Title:||High-dose methylprednisolone in the treatment of active ulcerative colitis.|
|Keywords:||Acute Disease, Adolescent, Adult, Aged, Aged, 80 and over, Colitis, Ulcerative, Drug Administration Schedule, Female, Humans, Male, Methylprednisolone, Middle Aged, Pilot Projects|
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