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High-dose methylprednisolone in the treatment of active ulcerative colitis.

Rosenberg, W; Ireland, A; Jewell, DP; (1990) High-dose methylprednisolone in the treatment of active ulcerative colitis. J Clin Gastroenterol , 12 (1) pp. 40-41.

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Abstract

Twenty patients with severe active ulcerative colitis were entered into a pilot study to test the efficacy of pulsed high-dose methylprednisolone in inducing remission. Of 20 patients, 12 improved, but 8 of 20 patients (40%) who did not went for urgent colectomy. The group proceeding to surgery tended to have more extensive disease. These results contrast unfavorably with historical control data from this unit.

Type: Article
Title: High-dose methylprednisolone in the treatment of active ulcerative colitis.
Location: UNITED STATES
Keywords: Acute Disease, Adolescent, Adult, Aged, Aged, 80 and over, Colitis, Ulcerative, Drug Administration Schedule, Female, Humans, Male, Methylprednisolone, Middle Aged, Pilot Projects
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)
URI: http://discovery.ucl.ac.uk/id/eprint/1340633
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