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Detection of aneuploidy by array comparative genomic hybridization using cell lines to mimic a mosaic trophectoderm biopsy.

Mamas, T and Gordon, A and Brown, A and Harper, J and Sengupta, S (2012) Detection of aneuploidy by array comparative genomic hybridization using cell lines to mimic a mosaic trophectoderm biopsy. Fertil Steril , 97 (4) 943 - 947. 10.1016/j.fertnstert.2011.12.048.

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Abstract

To examine the effect of mosaicism in the array comparative genomic hybridization result during preimplantation genetic screening after blastocyst biopsy.

Type:Article
Title:Detection of aneuploidy by array comparative genomic hybridization using cell lines to mimic a mosaic trophectoderm biopsy.
Location:United States
DOI:10.1016/j.fertnstert.2011.12.048
Language:English
Keywords:Aneuploidy, Biopsy, Cell Line, Chromosomes, Human, Comparative Genomic Hybridization, Ectoderm, Female, Genetic Testing, Humans, Mosaicism, Predictive Value of Tests, Preimplantation Diagnosis, Trophoblasts
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Women's Health > Reproductive Medicine

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