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A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease

Cummings, DM; Alaghband, Y; Hickey, MA; Joshi, PR; Hong, SC; Zhu, C; Ando, TK; ... Levine, MS; + view all (2012) A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease. JOURNAL OF NEUROPHYSIOLOGY , 107 (2) pp. 677-691. 10.1152/jn.00762.2011.

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Type: Article
Title: A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease
DOI: 10.1152/jn.00762.2011
Keywords: Science & Technology, Life Sciences & Biomedicine, Neurosciences, Physiology, Neurosciences & Neurology, electrophysiology, synaptic currents, NMDA receptors, aggregates, behavior, LARGE TRINUCLEOTIDE REPEAT, STRIATAL NEURONAL LOSS, TRANSGENIC MICE, EARLY MOTOR, CORTICOSTRIATAL PATHWAY, BEHAVIORAL DEFICITS, SPINY NEURONS, DYSFUNCTION, MUTATION, ONSET
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology
URI: http://discovery.ucl.ac.uk/id/eprint/1335065
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