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Evaluation of methotrexate and corticosteroids for the treatment of localized scleroderma (morphoea) in children.

Weibel, L; Sampaio, MC; Visentin, MT; Howell, KJ; Woo, P; Harper, JI; (2006) Evaluation of methotrexate and corticosteroids for the treatment of localized scleroderma (morphoea) in children. Br J Dermatol , 155 (5) 1013 - 1020. 10.1111/j.1365-2133.2006.07497.x.

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Abstract

Localized scleroderma (LS) or morphoea is often considered to be a benign self-limiting condition confined to the skin and subcutaneous tissue. However, the course of the disease is unpredictable and severe functional and cosmetic disability may result. Drug treatment with systemic corticosteroids in combination with methotrexate has been reported to be beneficial in LS, but data in children is limited.

Type:Article
Title:Evaluation of methotrexate and corticosteroids for the treatment of localized scleroderma (morphoea) in children.
Location:England
DOI:10.1111/j.1365-2133.2006.07497.x
Language:English
Keywords:Adolescent, Child, Child, Preschool, Dermatologic Agents, Disease Progression, Drug Evaluation, Drug Therapy, Combination, Female, Follow-Up Studies, Glucocorticoids, Humans, Male, Methotrexate, Prednisolone, Recurrence, Retrospective Studies, Scleroderma, Localized, Thermography, Treatment Outcome
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Infection and Immunity (Division of)
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)
UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Child Health > Department of Infection and Immunity > ICH - Molecular Immunology Unit

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