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A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de Pointes

Kaeaeb, S; Crawford, DC; Sinner, MF; Behr, ER; Kannankeril, PJ; Wilde, AAM; Bezzina, CR; ... Roden, DM; + view all (2012) A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de Pointes. CIRCULATION-CARDIOVASCULAR GENETICS , 5 (1) pp. 91-99. 10.1161/CIRCGENETICS.111.960930.

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Type: Article
Title: A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de Pointes
DOI: 10.1161/CIRCGENETICS.111.960930
Keywords: Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Genetics & Heredity, Cardiovascular System & Cardiology, candidate genes, death, sudden, SNP, torsade de pointes, adverse drug events, LONG-QT SYNDROME, REDUCED REPOLARIZATION RESERVE, MULTILOCUS GENOTYPE DATA, INTERVAL DURATION, CARDIOVASCULAR DRUGS, COMMON VARIANTS, HUMAN GENOME, I-KS, POPULATION, PROLONGATION
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
URI: http://discovery.ucl.ac.uk/id/eprint/1332681
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