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Long-QT syndrome and torsades de pointes in a patient with Takotsubo cardiomyopathy: an unusual case

Mahida, S; Dalageorgou, C; Behr, ER; (2009) Long-QT syndrome and torsades de pointes in a patient with Takotsubo cardiomyopathy: an unusual case. EUROPACE , 11 (3) 376 - 378. 10.1093/europace/eun336.

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Abstract

Takotsubo cardiomyopathy is a syndrome characterized by transient left ventricular apical ballooning associated with electrocardiogram (ECG) changes and minimal myocardial enzymatic release, mimicking acute myocardial infarction in patients without significant coronary disease at angiography. We report an unusual case of a patient who presented with Takotsubo cardiomyopathy associated with long-QT syndrome and who developed cardiac arrest secondary to torsades de pointes.The relationship between Takotsubo cardiomyopathy and abnormal repolarization has been well documented. Despite this, there have been few reports of malignant ventricular arrhythmias or sudden death. This report suggests that prolongation of QTc interval in Takotsubo cardiomyopathy may not be as benign as previously suggested but may in fact uncover an abnormality of repolarization that may be genetic in basis and carry a risk of sudden death.

Type:Article
Title:Long-QT syndrome and torsades de pointes in a patient with Takotsubo cardiomyopathy: an unusual case
DOI:10.1093/europace/eun336
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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