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Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2.

Khan, WS; Tew, SR; Adesida, AB; Hardingham, TE; (2008) Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2. Arthritis Res Ther , 10 (4) R74 - ?. 10.1186/ar2448.

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Abstract

Infrapatellar fat pad (IPFP) is a possible source of stem cells for the repair of articular cartilage defects. In this study, adherent proliferative cells were isolated from digests of IPFP tissue. The effects of the expansion of these cells in fibroblast growth factor-2 (FGF-2) were tested on their proliferation, characterisation, and chondrogenic potential.

Type:Article
Title:Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2.
Location:England
DOI:10.1186/ar2448
Language:English
Additional information:PMCID: PMC2575620
Keywords:Adipose Tissue, Antibodies, Monoclonal, Cell Differentiation, Cell Proliferation, Cell- and Tissue-Based Therapy, Cells, Cultured, Chondrogenesis, Fibroblast Growth Factor 2, Growth Substances, Humans, Mesenchymal Stromal Cells, Patella, Pericytes, Rheumatic Diseases
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of)

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