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Antiphospholipid syndrome

Austin, S; Cohen, H; (2010) Antiphospholipid syndrome. Medicine , 38 (2) pp. 101-104. 10.1016/j.mpmed.2009.10.012.

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Abstract

Antiphospholipid syndrome (APS) is an autoimmune disorder in which autoantibody production can lead to a hypercoagulable state, pregnancy failure and/or a multitude of other systemic manifestations. In recent times, research into the antiphospholipid antibodies has increased our understanding of the pathogenic process and encouraged improved detection of antiphospholipid antibodies. However, the precise nature of the pathology of APS remains challenging, as does the management of this disorder. This review outlines the key features of APS, including the laboratory tests and their interpretation, and offers advice regarding the management of patients with APS both in the medical and obstetric settings. © 2009 Elsevier Ltd. All rights reserved.

Type: Article
Title: Antiphospholipid syndrome
DOI: 10.1016/j.mpmed.2009.10.012
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology
URI: http://discovery.ucl.ac.uk/id/eprint/1331551
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